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Results of the m-RESIST feasibility study. A Mobile therapeutic attention for treatment-resistant schizophrenia

Authors:

Eva Grasa ,

Institut d'Investigació Biomèdica Sant Pau (IIB Sant Pau), Barcelona; Biomedical Research Networking Center for Mental Health Network (CIBERSAM), ES
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Anna Alonso-Solís,

Institut d'Investigació Biomèdica Sant Pau (IIB Sant Pau), Barcelona; Biomedical Research Networking Center for Mental Health Network (CIBERSAM), ES
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Katya Rubinstein,

The Gertner Institute of Epidemiology and Health Policy Research, Sheba Medical Center, Tel-Aviv University, IL
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Asaf Caspi,

The Gertner Institute of Epidemiology and Health Policy Research, Sheba Medical Center, Tel-Aviv University, IL
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Kinga Farkas,

Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, HU
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Zsolt Unoka,

Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, HU
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Susana Ochoa,

Biomedical Research Networking Center for Mental Health Network (CIBERSAM); Parc Sanitari Sant Joan de Déu, Sant Boi Llobregat, Barcelona, ES
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Elena Huerta-Ramos,

Biomedical Research Networking Center for Mental Health Network (CIBERSAM); Parc Sanitari Sant Joan de Déu, Sant Boi Llobregat, Barcelona, ES
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Jussi Seppälä,

University of Oulu, Centre for Life Course Health Research, Oulu, Finland and Department of Psychiatry, Oulu University Hospital, FI
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Erika Jääskeläinen,

University of Oulu, Centre for Life Course Health Research, Oulu, Finland and Department of Psychiatry, Oulu University Hospital, FI
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Cari Almazán,

Agency for Health Quality and Assessment of Catalonia (AQuAS), ES
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Johanna Caro Mendivelso,

Agency for Health Quality and Assessment of Catalonia (AQuAS), ES
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Anna Triantafillou,

Athens Technology Center (ATC), Athens, GR
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Panagiotis Kokkinakis,

Athens Technology Center (ATC), Athens, GR
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Shenja Van Der Graaf,

Imec-SMIT, Vrije Universiteit Brussel, BE
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Charlotte Jewell,

Imec-SMIT, Vrije Universiteit Brussel, BE
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Jesús Berdún,

TicSalut Health Department, Generalitat de Catalunya, ES
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Elisenda Reixac,

TicSalut Health Department, Generalitat de Catalunya, ES
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Iluminada Corripio

Institut d'Investigació Biomèdica Sant Pau (IIB Sant Pau), Barcelona; Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Madrid, ES
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Abstract

In the European Union between 0.2 and 2.6% of the population suffer from psychotic disorders, and around 40% can be considered resistant to pharmacological treatment [1]. Interventions based on m-Health solutions may be effective in increasing treatment adherence, relieving some of the symptoms of schizophrenia and thus, preventing relapses. Although smartphone ownership among people with schizophrenia is relatively high and increasing, to date, mHealth studies have not been performed in Treatment Resistant Schizophrenia (TRS) samples. In this study, we present the results of the m-RESIST feasibility project (www.mresist.eu), a new therapeutic program based on novel technology.). The aim of the m-RESIST study is to assess acceptability, usability and user experience, satisfaction and empowerment after using the m-RESIST solution.

Thirty-nine TRS patients, 11 caregivers and 8 clinicians were recruited for the study, which was  carried out in Gertner Institute (Tel-Aviv, Israel), Semmelweis University (Budapest, Hungary) and Hospital de la Santa Creu i Sant Pau (Barcelona, Spain). Acceptability was measured with an adapted version to TRS patients of TAM questionnaire (7-point Likert scale). [2]. Satisfaction and empowerment was measured with CSQ-8 [3] and BUES [4] scales respectively. In order to yield insights into user experience a questionnaire was developed and administered at the start, in the middle and at the end of the pilot.

Results showed that patients’ acceptance of m-RESIST ranged from moderate to high, with a mean score for perceived use and ease of use 5.16 and 5.36, respectively. In general, patient’s satisfaction was good: 57% thought that the quality of service was good or excellent. 65% of patients reported having the services they wanted and 43% thought that the program met their needs. However, 19% did not get the kind of service they wanted and for 38% only few of their needs were met. 78% of the sample was overall satisfied with m-RESIST and 70% would come back again to it. In terms of user experience, patients indicated that m-RESIST solution permits an easier and a quicker communication with clinicians. Patients also reported that the feeling of having a clinical team involved and concerned din their wellbeing made them feel more protected. Caregivers reported that m-RESIST provided a better support for patients and a better follow-up, and also were unanimous about the sense of security. Clinicians indicated that the m-RESIST system was easy and intuitive to use and felt that it opened up a new communication pathway with their patients. Finally, the result of empowerment in our patients was 2.76, out of a possible score of 4, which indicates a high level of empowerment Mean for dropouts was 20%.

To conclude, in terms of acceptability, usability and satisfaction, the m-RESIST solution was well accepted by patients, caregivers and clinicians. These results offer an encouraging starting point concerning the use of ICT tools in the treatment of TRS patients.

m-RESIST project is founded by Horizon 2020 Framework Programme of the European Union. Co-financed with European Union ERDF Funds.

How to Cite: Grasa E, Alonso-Solís A, Rubinstein K, Caspi A, Farkas K, Unoka Z, et al.. Results of the m-RESIST feasibility study. A Mobile therapeutic attention for treatment-resistant schizophrenia. International Journal of Integrated Care. 2019;19(4):16. DOI: http://doi.org/10.5334/ijic.s3016
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Published on 08 Aug 2019.

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