Abstract
Purpose: To assess the effect of routine use of home telemonitoring on the risk of re-admission to hospital amongst patients with heart failure.
Context: Heart failure is a common reason for hospitalizations, which often recur. Telemonitoring might detect early decompensation allowing intervention to prevent re-admission. A systematic review concluded that telehealth reduced heart failure related hospitalizations by almost 30 % [1]. In Europe, the use of telehealth has primarily been limited to studies, pilots and small programs; it has not yet become routine in clinical practice. Accordingly, we assessed the effects of a telemonitoring service on unplanned re-admissions to hospital at 90 days and one year.
Methods: OPERA-HF is an ongoing prospective observational study, enrolling patients hospitalized with worsening heart failure to the Hull & East Yorkshire Hospitals NHS Trust, UK. All patients enrolled in the study are followed subsequent to discharge. The primary outcome for this analysis was unplanned all-cause readmission. Patients were referred to telehealth by the hospital discharge team if aged >18 years and registered with a Hull-based primary care physician. To remove imbalances in baseline characteristics between patients on telehealth and those not, propensity matching was used to estimate effectiveness. A logistic regression model was used to determine the propensity score (probability of being selected for telehealth) for each patient. The calculated propensity scores were applied to a weighted logistic regression to account for selection assignment differences between patients on telehealth and on standard care. Propensity scores were calculated by controlling for age, number of severe comorbidities, New York Heart Association (NYHA) class at admission, emergency heart failure hospitalizations in prior 6 months, total daily pill count, heart rate and NT-proBNP at discharge.
Results and discussion: Of 546 patients enrolled, 89 received telehealth. Table 1 shows their baseline characteristics. Patients selected for telehealth had fewer unplanned readmissions at both 90 days (OR: 0.66; 95% CI: 0.45 to 0.97; P < 0.05) and one year (OR: 0.68; 95% CI: 0.46 to 0.99; P < 0.05) than those who were not. In a routine care setting, patients with heart failure receiving telehealth after discharge have fewer unplanned readmissions compared with those without telehealth.
Characteristic | w/o Telehealth (N=457) | with Telehealth (N=89) | All (N= 546) |
| Valid N | Summary | Valid N | Summary | Valid N | Summary |
Age, year | 457 | 77 [68 – 83] | 89 | 73 [66 – 80] | 546 | 76 [68 – 82] |
Number of severe comorbidities, sum | 457 | 1 [1 -2] | 89 | 2 [1 -2] | 546 | 1 [1 - 2] |
More than one unplanned HF hospitalizations in prior 6 months, yes | 457 | 70 (15%) | 89 | 14 (16%) | 546 | 84 (15%) |
Total daily pill count at discharge, sum | 386 | 11 [9 -16] | 84 | 13 [9 -16] | 470 | 12 [9 - 16] |
NYHA at admission: Class I/II, yes NYHA at admission: Class III, yes NYHA at admission: Class IV, yes | 307 | 40 (13%) 199 (65%) 68 (22%) | 80 | 7 (9%) 52 (65%) 21 (26%) | 387 | 47 (12%) 251 (65%) 89 (23%) |
Heart Rate at discharge, bpm | 283 | 75 [66 – 89] | 68 | 75 [68 – 82] | 351 | 75 [67 – 88] |
NT-proBNP at discharge, pg/mL | 340 | 4828[1972- 10710] | 67 | 5097 [2930 - 8714] | 407 | 4891 [2112 - 10500 ] |
90 day unplanned readmission, yes | 457 | 151 (33%) | 89 | 25 (28%) | 546 | 176 (32%) |
1 year unplanned readmission, yes | 396 | 221 (56%) | 78 | 41 (53%) | 474 | 262 (55%) |
Table 1 Baseline characteristics stratified by being on Tele health or not. Characteristics are summarized by their count and fraction (N (%)) for categorical or their median and interquartile range (Median [25th – 75th]) for continuous variables, respectively
References:
[1] Inglis SC, Clark RA, Dierckx R, Prieto-Merino D, Cleland JGFet al., 2015, Structured telephone support or non-invasive telemonitoring for patients with heart failure, COCHRANE DATABASE OF SYSTEMATIC REVIEWS, ISSN: 1469-493X
Published on
09 Nov 2016.
