Introduction: Intergenerational cycles of poverty, violence and crime, poor education and employment opportunities, psychopathology, and poor lifestyle and health behaviours require innovative models of health care delivery to break them. We describe a programme of research informed service development targeting vulnerable families in inner metropolitan Sydney, Australia that is designed to build and confirm a “Theory of Neighbourhood Context, Stress, Depression, and the Developmental Origins of Health and Disease (DOHaD)”. We describe the development of an intervention design and business case that drew on earlier realist causal and programme theoretical work.
Methods: Realist causal and programme theory were used to inform the collaborative design of initiatives for vulnerable families. The collaborative design process included: identification of desirable and undesirable outcomes and contextual factors, consultation forums, interagency planning, and development of a service proposal.
Results: The design elements included: perinatal coordination, sustained home visiting, integrated service model development, two place-based hubs, health promotion and strengthened research and analysis capability.
Conclusions: We demonstrate here the design of interventions for vulnerable families in Sydney utilising translational research from previous realist causal and program theory building to operational service design. We have identified the importance of our earlier analysis of underlying causal mechanisms and related programme mechanisms for identifying the elements for the full intervention design. The application of theory added rigour to the design of the integrated care initiatives. In applying the theory to the local situation the analysis took into account: the role of the local agencies; evidence of program effectiveness; determinants and outcomes for local children and their families; the current deployment of service resources; and insights from front-line staff and interagency partners.
Inequities in the health and wellbeing of Australian children and families who live in disadvantaged communities are growing [1, 2, 3], despite a range of government initiatives designed to alleviate the impact of disadvantage and social exclusion .
Key to this is the issue of how we break the intergenerational cycles of poverty, violence and crime, poor education and employment opportunities, psychopathology, and poor lifestyle and health behaviours (including: unhealthy nutrition and physical activity, tobacco and substance use, interpersonal violence, early and unprotected sexual activity) . Longitudinal cohort studies, some for three generations, have identified intergenerational transmission of psychopathology, poor parenting practices and family dysfunction that contribute poor health outcomes throughout the life course (including: suicide, teen age pregnancy, obesity, depression, tobacco smoking, diabetes and cardiovascular disease) . Implicated as predictors of intergenerational transmission are: child abuse, harsh parenting practices and socio-economic disadvantage [7, 8, 9].
Increased understanding of the complex and inter-related issues that contribute to poor outcomes for vulnerable disadvantaged families have prompted concern from researchers and service providers about the often fragmented and inefficient service response, one that is not specific to local community needs . This has prompted an increased policy commitment to community-led, multi-disciplinary, cross-sector integrated service delivery [11, 12]. There is limited research on how to design or build an evidence-informed integrated response to complex social problems.
Critical realism offers an approach to empirically inform theory building and collaborative design of social interventions [13, 14]. As a philosophy of science, it contends that there is a natural and social reality that exists independently of empirical observation and human thought. Those unobservable structures and mechanisms, under certain conditions, cause the observed events, and can be discovered and understood. Thus critical realism requires an understanding of the social situation or context, and requires the investigation of underlying mechanisms (causes) behind the observed events. In the study and practice of integrated care, the critical realist approach requires the inclusion of an analysis of pre-existing structures and mechanisms that may be contributing to the observed maternal, child and family outcomes , followed by an analysis of how an intervention may work to produce the desired change in observed outcomes.
It is well recognised that the early years play an important role in the genesis of later adult health and disease. Current theory construction is focused on how various genetic and environmental mechanisms interact to influence life course outcomes. The environments implicated are: intrauterine, the maternal-infant dyad, family and household life, and external social and physical environments” . Our critical realist theory building analysis  used the theoretical frames of: Stress Process; Social Isolation; Social Exclusion; Social Services; Social Capital, Acculturation Theory and Global-economic level mechanisms to explain our observed inequities in maternal outcomes. In our previously reported analysis stress was identified as the underlying “necessary mechanism” that has the tendency to cause several of the observed outcomes including depression, anxiety, and health harming behaviours (Figure 1) . Our ecological and multilevel empirical studies supported the theoretical proposition that neighbourhood adversity causes maternal psychological distress and depression within the context of social buffers including social networks, social cohesion and social services . The theoretical causal propositions from that body of work were subsequently used to generate programme theory which was used in the design study reported here [19, 20].
Metropolitan Sydney has been described as being “a city divided” [21, 22, 23, 24, 25] with social disadvantage clustered in the southern and western districts. Local perinatal and paediatric social epidemiology studies have further identified socially deprived neighbourhoods and populations with poor perinatal, child and family outcomes [26, 27, 28, 29]. Within Sydney Local Health District (SLHD), located in Central and Inner West Sydney, the clustering of social disadvantage and poor perinatal, child and family outcomes is evident in the Cities of Canterbury, Marrickville and Sydney .
The SLHD was established in 2011 and the following year the District commenced a programme of collaborative interagency work to address the needs of children, young people and their families. An early focus of that work was on the special needs of families living with increased psychological and social stress. This paper will describe the development of an intervention design and business case that drew on our earlier realist causal and programme theoretical work and is part of a program of research and programme development that seeks to build and confirm a theory of “Neighbourhood Context, Stress, Depression, and the Developmental Origins of Health and Disease (DOHaD)”. The work was undertaken from 2010 to 2014.
The overall research design is a longitudinal, multilevel, critical realist evaluation of applied programme interventions. The longitudinal dimension involves repeated measures of the output, produced after implementing the program, at different points in the course of the program running (time 1, time 2, time 3). The multilevel aspect incorporates the investigation of different levels of mechanisms operating at the psychological level of self, the level of situated activity, and the levels of intermediate and macro level services. The intervention initiatives, responding to the conceptual framework (Figure 1), were designed and implemented by interagency and community collaborations. In doing this we aimed to move from “explaining underlying social mechanisms to generate social interventions in partnership with the affected populations” .
The main research programme comprised of four phases (Figure 2). The methodology used for the four phases was reported separately . In summary the four phases are: 1) operationalisation of programme theory and intervention development and planning; 2) evaluation of the interventions; 3) theory testing studies; and 4) dissemination of the findings. In this paper we report on one of the collaborative design projects undertaken in Phase 1: Operationalisation.
Critical realist philosophy of science seeks to discover the underlying mechanisms (M) that cause an empirically observed event or outcome (O). The idea that an event will not always follow from a causal mechanism, in an open system, is called a tendency, where the contextual conditions for the mechanisms to operate may not exist. Thus it is important that the nature of the pre-existing conditions be examined. Critical realism also holds that reality is stratified so that each level has its own mechanisms and it is the existence of these level-specific mechanisms that constitute or define a level. The ability of mechanisms to combine to create something new is called emergence. Layder  illustrated this layering of reality in his Research Map (Figure 3). In this study we will use the following modification of the levels proposed by Layder , namely, Self, Situated Activity, Setting -Intermediate Level Social Organisation and Context – Macro Level Social Organisation. Mechanisms, emergence, a hierarchy of levels, and pre-existing historical conditions are all central to the critical realist design process described here.
Realist causal propositions are expressed in terms of mechanisms (M), context (C), and outcomes (O). The MCO propositions in our previously reported theory  are in the MCO form proposed by Danermark and colleagues . For evaluation studies, Pawson and Tilley  have proposed a CMO configuration. In realist programme evaluation terminology the mechanism (M) is an intervention mechanism (IM), and not a causal mechanism. Denyer and colleagues  draw attention to the importance of specifying the intervention separate from the mechanism and proposed the use of a CIMO-logic (Context, Intervention Mechanism, Outcome). Thus a CIMO is a hypothesis that the programme theory produces a change (O) because of the action of an intervention (I) on an underlying mechanism (M) operating in particular contexts (C). We will use the CIMO logic in this study and will apply it to the development of the Theory of Change (ToC) logic model (Figure 6).
Realist programme evaluation usually starts with a programme that has been already designed. The approach assumes that whenever a programme is implemented it is testing an existing programme theory consisting of realist programme hypotheses (CMOs). The process of designing a programme intervention using realist causal and programme theory is not well explicated. For the purposes of this study we have drawn on the work of Keller and colleagues  who present a realist design-evaluation framework that combines design theory and realist evaluation.
The collaborative design of the integrated care initiative involved: 1) planning forums; 2) shared outcome planning; 3) collaborative interagency planning; and 4) preparation of a fully funded business plan, Theory of Change and logic model.
The development of a Theory of Change using collective and collaborative processes can be difficult. We used the set of steps proposed by Mackenzie and Blamey :
The design analysis integrated our earlier causal and programme theoretical work, and collaborative design for vulnerable families. Consequently the critical realist theoretical framework guiding the collaborative effort incorporated 4 elements:
The planning undertaken here did not include human subjects. Ethical approval was not sought. The indicator reports used secondary data and did not require ethics approval. The earlier cited mixed method multilevel studies had ethics approval from the University of New South Wales.
At the level of service providers, the New South Wales (NSW) Government, Australia, introduced an interagency initiative for families in 1999. This was known as Families First. The aim of Families First was to support families and communities to care for children. The initiative drew on existing services and resources, and had a strong focus on coordinating a network of services. The initiative was later renamed Families NSW and has a foundation of local interagency groups supported by programme management groups (PMGs) at District levels. The Inner West Collaborative Programme Management Group (CPMG) plays a significant role in the planning of services for families within SLHD and is a pre-existing social structure with mechanisms that the present design initiative will aim to reconfigure.
At the service to consumers level, in 2009, an epidemiology report of child and family indicators was published that included information on the health and wellbeing of children and families living in both south western and inner west regions of Sydney . In preparation for the design work described here that report was updated in 2013 for Sydney LHD . Secondary analysis from the child and family indicator data-sets was made available for participants of the Vulnerable Children’s Forum and the Supporting Children and Families Forum. That analysis focused in detail on data available for each of the LGAs in SLHD, and was supplemented by a SLHD population needs analysis, and concurrent reviews of perinatal coordination and Infant of Substance Abusing Mothers (ISAM) Pathways .
The updated Child and Family Health Indicator Report: Inner West Sydney 2013  and results from Vulnerable Children’s Forum 2013 highlighted the challenges faced by service consumers in the Inner West Sydney District context and the service gaps that service providers needed to take into account, respectively. Findings from the recently completed study of “Neighbourhood Context, Stress, Depression, and the Developmental Origins of Health and Disease (DOHD)”  which elaborated realist causal and program theory were also included. That study was undertaken in the neighbouring South Western Sydney local government areas of Bankstown, Fairfield, Liverpool and Campbelltown. Those information sources, in combination, provided information and supported theories about the presenting contextual conditions [C] as shown in Figure 4 below. The analysis of contextual conditions uses a modification of the four levels proposed by Layder .
As earlier mentioned, two consultation forums were held. While the Vulnerable Children’s Forum highlighted service gaps in the context of interest, the Supporting Children and Families Forum 2014, contributed to the collaborative design by identifying the desirable service provision. The planning framework included assessment of: 1) the role of the health sector and SLHD, 2) scientific and economic evidence of program effectiveness; 4) determinants and outcomes of SLHD child health and development; 4) current deployment of SLHD resources; 5) current system performance; and 6) insights from front-line staff and interagency partners. A summary of the outcomes of the 2014 forum is shown below (Figure 5).
In response to the contextual analyses and consultation forums, a design initiative was formulated which formed the proposed interventions [I].
Three scientifically supported solutions were identified as possible solutions to disrupt the intergenerational cycles of disadvantage observed in SLHD:
Two Programme Logic supported solutions were also identified to support sector wide delivery:
The design elements were developed for inclusion in: 1) a Vulnerable Family Business Case, and 2) Child and Family Health Planning Priorities (Table 1).
|Design Component||Business Case||Child and Family Health Planning Priorities|
|Sustained Home Visiting (SHV)||
|Family and Community Integrated Service Development (FCISD)||
|Infrastructure Support (IS)||
The design elements arising from the collaborative design were informed by sound theoretical propositions regarding the underlying programme mechanisms. The programme theory concerns itself with specifying the potential psychological, motivational and behavioural outcomes produced by interventions at each level or layer.
The programme theory in Table 2 below is expressed in realist terms as context-intervention-mechanism and outcome (CIMO) conjectures. The first 2 columns in Table 1 below highlight the pre-existing Contextual Elements [C] and the prevailing causal mechanisms therein [CM]. The third to fifth columns highlight the proposed intervention [I], the intervention programme mechanisms [MP] and the anticipated outcomes [O] resulting, in response to the intervention. The categorised rows indicate how proposed elements of the intervention will work in configuration with each level of the context identified (Self, Situated Activity, Intermediate Level and Macro Level) using the levels or layers proposed by Layder  (Figure 3).
|Theorised Contextual Conditions (Figure 2)[C]||Present contextual mechanisms activated [CM]||Proposed Intervention Design Elements (Table 1)[I]||Postulated Intervention Programme Mechanisms(Table 1)[MP]||Postulated psychological, motivational and behavioural Outcomes [O]|
|Self – Self-identity and individuals experience|
|Lack of partner and family support, Distrust of services, Limited treatment access||Stress mechanism activated causing anxiety and depression||Friendship and family support, Professional support, Medication, Treatment||Activate mediating mechanisms of family, peer and professional support to strengthen and build trusting relationships with peers, family and clinicians through SHV and FCISD Design Components.||Decreased depression and anxiety|
|Lifetime trauma, Loss, Being alone, Isolation||Stress mechanism activated arising from mismatched expectations, and loneliness||Family and peer support, Home visiting, Telephone support||Increased perceived support|
|Situated Activity – Face to Face activity|
|Services unavailable or poor access, Services not trusted, Services not skilled||Absence of trusted professional support mechanism||“wrap around” services, Family Conferences, Workforce training||Activate services mechanisms that are client, peer and neighbourhood focused, and trauma and evidence informed through FCISD and IS Design Components.||Improved perceived access to skilled and trusted services|
|Community distrust, Low social capital and cohesion, crime, unemployment||Absence of trusted neighbourhood and community support mechanism||“wrap around” services, Family Conferences, Public health, Social work services||Improved perceived support from neighbours and community|
|Intermediate Level social and service organisation|
|Unhelpful intake and referral practices, Lack of service, knowledge and trust||Absence of specialist service support mechanism for front-line professionals||Strengthened pathways and design Collocation of services||
Activate mechanisms related to trust and confidence with service network, increased local social capital, community trust and community safety
Activate mechanisms relating to improved coordination and access to services and information through FCISD and IS Design Components.
|Improved perceived access to services that are “wrapped” around front-line workers|
|Weak social networks, community trust, community safety, available social services, access to information||Social level stress mechanisms relating to class, position, racism, segregation, crime and neighbourhood decay are activated tending to increase psychological stress||Population and community level interventions in neighbourhoods and communities||Decrease in psychological stress of individuals and families|
|Macro Level social and service organisation|
|Migration, Mega-malls pull service activity away from neighbourhoods, Urban development||Activation of social level stress mechanisms tend to hinder the activation of social level buffer mechanisms||Population and community level interventions in neighbourhoods and communities||
Activate mechanisms related to increased social level activities in deprived neighbourhoods.
Activate mechanisms related to increased migrant related social activities among ethnic populations through FCISD and IS Design Components.
|Increase in perceived social level buffers|
|Immigration policy, Racism, Media policy, Global market, Settlement patterns, Ethnic bonding networks, Access to services||Migrant related social level mechanisms including acculturation, cultural practices and integration tend to decrease social level stress||Ethnic and cultural specific community and population level interventions||Increase in perceived migrant social level buffers|
The ToC Logic Model (Figure 6) outlines the hypothesised links between the underlying programme mechanisms (programme theory), the intervention activities (implementation theory), and how they are anticipated to work in synergy to bring about desired outcomes .
The ToC Logic model was constructed following steps recommended by Mackenzie and Blamey . Those steps are:
We have used critical realist meta-theory to assist in the translation of previously reported empirical explanatory theory building to theory driven interventions. In so doing we have aimed to move from identifying and explaining the underlying social and psychological causal mechanisms, toward generating evidence-informed social interventions in partnership with the affected populations.
We demonstrate the design of interventions for vulnerable families in Sydney utilising translational research from previous realist causal and program theory building to operational service design. For example, previously developed propositions about the underlying mechanisms that cause maternal stress (i.e. loneliness and lack of trust) were used to develop propositions regarding programme mechanisms (i.e. trusting relationships) and design elements (i.e. sustained home visiting) that might buffer this effect.
Local quantitative and qualitative studies were used together with consultation forums and collaborative design approaches. Central to the development of the collaborative design reported here was the infrastructure provided by a network of interagency collaborative groups established as part of the earlier Families NSW initiative. Both consultative forums contributed to the development of shared long-term and interim outcomes and the identification of activities that if put in place could realise those outcomes. Resources necessary to initiate those activities were identified and included into a health sector business plan.
The critical realist approach requires the inclusion of an analysis of pre-existing structures and mechanisms that may be contributing to the observed maternal, child and family outcomes . The use of research findings from neighbouring South Western Sydney introduced a weakness into the design process which was only partly offset by the local forum, stakeholder interviews and the perinatal drug health study . A further limitation of the analysis and design elements was the strong health sector focus despite the collective approach to planning. This weakness was partly attributable to significant restructuring of the NSW Departments of Education, and Family and Community Services, which was undertaken during the planning process.
The programme theory used to inform the intervention remains tentative and will require testing during the implementation phase. The design propositions developed followed the context-intervention-mechanism-outcome (CIMO) logic proposed by Denyer . We are not aware of this approaching being applied previously to the translation of causal theory to programme theory. We propose that the robustness of this approach be assessed as part of the evaluation of the design implementation.
In undertaking this study we identified the importance of our earlier analysis of underlying causal mechanisms and related programme mechanisms for identifying the elements for the full intervention design. The application of theory added rigour to the design of the integrated care initiatives. In applying the theory to the local situation the analysis took into account: the role of the local agencies; evidence of program effectiveness; determinants and outcomes for local children and their families; the current deployment of service resources; and insights from front-line staff and interagency partners.
CPMG: Collaborative Programme Management Group, DOHaD: Developmental Origins of Health and Disease, CMO: Context, Mechanism, Outcome, CIMO: Context, Intervention, Mechanism, Outcome, ISAM: Infant of Substance Using Mother, NSW: New South Wales, SHV: Sustained Home Visiting, SLHD: Sydney Local Health District, ToC: Theory of Change, TDE: Theory Driven Evaluation.
Roelof Ettema PhD, Principal Lecturer Institute for Nursing Studies, Postdoc Researcher Chair Chronic Illnesses and Chair Methodology of Applied Sciences, HU University of Applied Sciences, Utrecht, The Netherlands.
One anonymous reviewer.
The authors have no competing interests to declare.
JE conceptualised the design and drafted the manuscript. LK provided critical and technical contribution. All authors read and approved the manuscript.
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